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Basolateral to apical flux (Papp) of FITC-labeled rat, mouse, human IgGs and chicken IgY across human FcRn and rat FcRn MDCK cells with a pH gradient (6.0/8.0). The inability of rodent IgG to bind to human FcRn was confirmed. Data is shown as mean ± SD; n = 3 (separate wells).
