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. 2017 Apr 3;9(5):792–800. doi: 10.1080/19420862.2017.1311435

Figure 5.

Figure 5.

Simulated VRC01 serum concentrations after steady-state is reached under different regimens of multiple-dose IV or SC VRC01. Panels A and B are for the 8-weekly 10 mg/kg and 30 mg/kg IV VRC01 regimens, respectively; Panels C and D are for the 2-weekly 5 mg/kg SC VRC01 regimens, with an IV loading dose of 10 mg/kg and 30 mg/kg, respectively. Lines show medians, and shaded areas show bands covered by the 2.5th and 97.5th percentiles for simulated concentrations. Simulated concentrations were computed from 1000 trials simulated using weight = 74.5 kg.