Table 3.

Spatial Extent of the Auditory Activation

Overall difference (ANOVA)
F-ratio	Prob
0.040	0.753
Means Comparison (Dunnett’s test)
Control	Drug	Difference	Lower CL	Upper CL	p-Value
Saline	Dexmedetomidine	272	−674	1219	0.893
Saline	Midazolam	246	−723	1215	0.922
Saline	Propofol	94	−853	1040	0.995

Drug comparison of change in cluster size (spatial extent of auditory activation) within the auditory cortex. The difference column is calculated by subtracting the cluster size change (sedation minus baseline) of each drug (dexmedetomidine, midazolam, propofol) from the cluster size change (repeat minus baseline) in the saline control group.