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. Author manuscript; available in PMC: 2018 Jul 10.
Published in final edited form as: Cancer Cell. 2017 Jun 22;32(1):57–70.e3. doi: 10.1016/j.ccell.2017.05.009

Figure 4. Mutation profiles and their functional consequences in Thai ICC and HCC.

Figure 4

(A) Overview distribution of mutation types in ICC (n=129) and HCC (n=68). (B) Plot of ranked nucleotide substitutions presented as single nucleotide variant (SNV) density per Mb for ICC and HCC. (C) Proportions (mean ±SEM with 95% confidence interval) of SNVs identified in ICC and HCC. Differences calculated by Students t-test (*p<0.05). (D) Proportions (percentage) of SNVs in ICC and HCC as separated by either transitions or transversions. (E) Number (mean ±SEM) of transition (C>T) or transversions (A>C, C>T, and C>A) in ICC and HCC according to subtypes. (F) Overview of SNV per sample (number of variant changes per sample) according to different subtypes. See also Tables S5 and S6.