Table 4.
Genotype distributions and allele frequencies of vitamin D receptor in patient groups with regards to associated microvascular complications.
| VDR polymorphism | Noncomplicated patients (n = 87) |
Complicated patients (n = 93) |
p value | OR (CI) |
|---|---|---|---|---|
| Fok 1 genotypes | ||||
| AA | 12 (13.8%) | 5 (5.4%) | Reference | |
| AG | 38 (43.7%) | 19 (20.4%) | 0.001 | 0.23 (0.07–0.6) |
| GG | 37 (42.5%) | 69 (74.2%) | 0.26 (0.1–0.5) | |
| Fok1 allele | ||||
| A (2n) | 62 (35.6%) | 29 (15.6%) | 0.001 | Reference |
| G (2n) | 112 (64.4%) | 157 (84.4%) | 2.9 (1.8–4.9) | |
| Bsm1 genotypes | ||||
| CC | 28 (32.2%) | 44 (47.3%) | 3.2 (1.3–7.7) | |
| CT | 36 (41.4%) | 38 (40.9%) | 0.02 | 2.2 (0.9–5.1) |
| TT | 23 (26.4%) | 11 (11.8%) | Reference | |
| Bsm1 alleles | ||||
| C (2n) | 92 (52.9%) | 126 (67.7%) | 0.003 | 1.8 (1.2–2.8) |
| T (2n) | 82 (47.1%) | 60 (32.3%) | Reference |
VDR, vitamin D receptor; OR, odds ratio; CI, confidence interval.