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. 2017 Jul 24;12(7):e0180951. doi: 10.1371/journal.pone.0180951

Table 3. Hazard ratios (95% Confidence interval) for incident CKD according to the FLI groups.

FLI P for trend
<30 30~59 ≥60
Incident CKD case 379 (13.12%) 224 (17.62%) 121 (20.13%) <0.001
Crude hazard ratios 1 1.418 (1.221~1.648) 1.723 (1.434~2.070) <0.0001
Model 1 1 1.260 (1.084~1.464) 1.690 (1.405~2.032) <0.0001
Model 2 1 1.175 (1.002~1.377) 1.468 (1.205~1.789) 0.0006
Model 3 1 1.170 (0.997~1.375) 1.459 (1.189~1.791) 0.0012

Model 1: Adjusted for age and sex. Model 2: Model 1 + further adjusted for baseline eGFR, smoking, regular exercise, alcohol intake, protein intake, systolic BP and DM. Model 3: Model 2 + further adjusted for total cholesterol and log hsCRP.