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. 2017 Jul 24;12(7):e0180818. doi: 10.1371/journal.pone.0180818

Table 3. Associations of BMI with total and cardiovascular mortality by age strata.

Non-Cardiovascular and Stroke Mortality Cardiovascular and Stroke Mortality
BMI categories Pop/deaths /1000 p-y Adj HR (95% C.I.) Pop/deaths /1000 p-y Adj HR (95% C.I.)
Whole cohort
 <18.5 (Underweight) 158/27 55.4 1.89 (1.12–3.20) 158/6 12.3 3.99 (0.96–16.58)
 18.5–22.9 (Normal weight) 1039/76 24.0 1.20 (0.80–1.81) 1039/16 5.1 2.73 (0.79–9.44)
 23.0–24.99(Normal-weight-II) 595/34 18.1 1 (referent) 595/3 1.6 1 (referent)
 25.0–27.49 (Overweight Pre-obese-I) 467/27 18.6 0.99 (0.60–1.65) 467/7 4.8 2.48 (0.63–9.70)
 27.5–29.99 (Overweight-Pre-obese-II) 224/15 22.1 1.28 (0.70–2.36) 224/2 2.9 1.89 (0.31–11.34)
 ≥30.0 (Overweight Obese Class I, II, III) 121/7 18.2 1.05 (0.47–2.39) 121/4 10.4 6.62 (1.45–30.11)
Middle-aged cohort, 55–64 years
 <18.5 (Underweight) 63/5 25.0 6.30 (1.65–24.07) 63/0 NA NA NA
 18.5–22.9 (Normal weight) 526/19 11.9 3.85 (1.29–11.49) 526/2 1.3 1.67 (0.14–20.48)
 23.0–24.99(Normal-weight-II) 295/4 4.3 1 (referent) 295/1 1.1 1 (referent)
 25.0–27.49 (Overweight Pre-obese-I) 225/6 8.6 2.23 (0.62–7.96) 225/1 1.4 1.92 (0.11–34.76)
 27.5–29.99 (Overweight-Pre-obese-II) 113/3 8.7 2.20 (0.48–10.03) 113/0 NA NA NA
 ≥30.0 (Overweight Obese Class I, II, III) 70/4 18.7 5.22 (1.26–21.60) 70/0 NA NA NA
Old cohort, 65+
 <18.5 (Underweight) 95/22 76.7 1.50 (0.84–2.67) 95/6 20.9 6.15 (1.19–31.68)
 18.5–22.9 (Normal weight) 513/57 36.3 0.93 (0.59–1.46) 513/14 8.9 3.53 (0.79–15.71)
 23.0–24.99(Normal-weight-II) 300/30 31.5 1 (referent) 300/2 2.1 1 (referent)
 25.0–27.49 (Overweight Pre-obese-I) 242/21 28.0 0.84 (0.48–1.47) 242/6 8.0 3.17 (0.63–15.93)
 27.5–29.99 (Overweight-Pre-obese-II) 111/12 36.0 1.17 (0.60–2.31) 111/2 6.0 2.91 (0.41–20.72)
 ≥30.0 (Overweight Obese Class I, II, III) 51/3 17.6 0.52 (0.16–1.72) 51/4 23.5 10.0 (1.80–55.67)

Covariates in in Cox regression model are: age (continuous), sex (men, women), education (≤6, >6 years), smoking, alcohol, physical activities