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(a) Simplicity region and SNV cluster errors dominated, constituting 219 and 172 of the HLFPs, respectively. Peripheral sequence read and base inversion errors were relatively rare. LFPs and LTPs comprised 126 and 156 of the ultrarare variants, respectively. (b) Of the 393 HLFPs, 354 were distinctly classified into 4 categories, and 39 variants met multiple criteria.
