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. Author manuscript; available in PMC: 2018 May 2.
Published in final edited form as: Structure. 2017 Apr 6;25(5):697–707.e4. doi: 10.1016/j.str.2017.03.002

Figure 1. Comparison of Cif’s interactions with EBH and EpH.

Figure 1

A. View of the active-site residues of the aligned structures, showing the overlay of the CifE153Q intermediates formed with EpH (yellow carbons) and EBH (blue carbons). Inset indicates a descriptive coordinate system used throughout this manuscript. B. View after 90° rotation of the structures, with the proto-diol bonds shadowed. C. Superposition and chemical diagrams of the proposed bound epoxides as inferred from these crystal structures. The black arrows indicate the carbon attacked by Asp129. D. Specific activity of rac-EpH and rac-EBH at a 2 mM concentration. Mean ± S.D.; **, p < 0.01. See also Figure S1.