Table 1.
Groups | Total Mankin | Tidemark integrity | Matrix staining | Cellularity | Structure |
---|---|---|---|---|---|
Control | 0.40 ± 0.03 | 0.00 | 0.16 ± 0.03 | 0.20 ± 0.03 | 0.04 ± 0.00 |
Cur | 0.38 ± 0.04 | 0.00 | 0.15 ± 0.40 | 0.19 ± 0.05 | 0.04 ± 0.00 |
Ncur | 0.38 ± 0.04 | 0.00 | 0.16 ± 0.80 | 0.18 ± 0.07 | 0.04 ± 0.00 |
MIA | 11.6 ± 1.60* | 0.80 ± 0.09* | 3.86 ± 0.60* | 3.20 ± 0.30* | 3.70 ± 0.60* |
Cur + MIA | 5.70 ± 0.30*† | 0.30 ± 0.07*† | 2.60 ± 0.04*† | 1.80 ± 0.80*† | 1.50 ± 0.50*† |
NCur +MIA | 1.70 ±0.20*†θ | 0.00 | 0.20 ±0.07*†θ | 0.60 ± 0.10*†θ | 0.90 ±0.06*†θ θ |
Values are expressed as mean ± SD for eight rats.
p < 0.001,
p < 0.01,
p < 0.01,
p < 0.001;
symbols, respectively, indicate comparison with control, mono-iodoacetate (MIA)-induced osteoarthritis (OA) and Cur group.