Table 1.

Mankin scoring of knee joints in control and experimental groups

Groups	Total Mankin	Tidemark integrity	Matrix staining	Cellularity	Structure
Control	0.40 ± 0.03	0.00	0.16 ± 0.03	0.20 ± 0.03	0.04 ± 0.00
Cur	0.38 ± 0.04	0.00	0.15 ± 0.40	0.19 ± 0.05	0.04 ± 0.00
Ncur	0.38 ± 0.04	0.00	0.16 ± 0.80	0.18 ± 0.07	0.04 ± 0.00
MIA	11.6 ± 1.60*	0.80 ± 0.09*	3.86 ± 0.60*	3.20 ± 0.30*	3.70 ± 0.60*
Cur + MIA	5.70 ± 0.30*†	0.30 ± 0.07*†	2.60 ± 0.04*†	1.80 ± 0.80*†	1.50 ± 0.50*†
NCur +MIA	1.70 ±0.20*†θ	0.00	0.20 ±0.07*†θ	0.60 ± 0.10*†θ	0.90 ±0.06*†θ θ

Values are expressed as mean ± SD for eight rats.

^* p < 0.001,

^† p < 0.01,

^θ p < 0.01,

^θθ p < 0.001;

^{*, † and θ} symbols, respectively, indicate comparison with control, mono-iodoacetate (MIA)-induced osteoarthritis (OA) and Cur group.