Table 2.
Percent of individuals with positive responses to questions in the SLE-specific portion of the Connective Tissue Disease Screening Questionnaire (SLE-CSQ).
| CSQ Response |
SLE, % n=3357 |
ILE, % n=432 |
HC, % n=1525 |
SLE vs. ILE OR (95%CI)P* |
ILE vs. HC OR (95%CI)P* |
SLE vs. HC OR (95%CI)P* |
|---|---|---|---|---|---|---|
| Cheek Rash | 55.6 | 51.2 | 4.0 | 1.2 (1.0–1.5) 0.080 |
25.1 (18.2–34.5) <0.0001 |
30.1 (23.0–39.2) <0.0001 |
| Discoid Lupus | 2.0 | 2.3 | 0.0 | 0.8 (0.4–1.6) 0.627 |
NC 0.970 |
NC 0.971 |
| Sun Sensitivity | 61.9 | 58.6 | 7.1 | 1.2 (0.9–1.4) 0.176 |
18.4 (14.0–24.1) <0.0001 |
21.1 (17.2–26.0) <0.0001 |
| Mouth Sores | 52.1 | 50.0 | 6.2 | 1.1 (0.9–1.3) 0.411 |
15.1 (11.4–20.0) <0.0001 |
16.4 (13.2–20.4) <0.0001 |
| Arthritis | 78.8 | 78.2 | 19.0 | 1.0 (0.8–1.3) 0.793 |
15.4 (11.8–20.0) <0.0001 |
15.9 (13.6–18.5) <0.0001 |
| Pleurisy | 58.2 | 51.9 | 9.0 | 1.3 (1.0–1.6) 0.012 |
10.9 (8.4–14.1) <0.0001 |
14.1 (11.7–17.0) <0.0001 |
| Protein in Urine | 65.1 | 50.0 | 9.0 | 1.9 (1.5–2.3) <0.0001 |
10.1 (7.8–13.1) <0.0001 |
18.9 (15.6–22.8) <0.0001 |
| Seizure | 19.4 | 14.4 | 2.8 | 1.4 (1.1–1.9) 0.012 |
5.9 (3.9–8.9) <0.0001 |
8.5 (6.2–11.6) <0.0001 |
| Low Blood Counts |
76.6 |
66.0 |
23.5 |
1.7 (1.4–2.1) <0.0001 |
6.3 (5.0–8.0) <0.0001 |
10.7 (9.3–12.3) <0.0001 |
| Positive ANA | 62.6 | 67.6 | 1.0 | 0.8 (0.6–1.0) 0.044 |
210 (122–363) <0.0001 |
169 (101–282) <0.0001 |
| Cold Sensitivity | 58.5 | 57.4 | 9.2 | 1.0 (0.8–1.3) 0.655 |
13.3 (10.3–17.3) <0.0001 |
14.0 (11.6–16.8) <0.0001 |
| Rapid Hair Loss |
52.2 |
47.2 |
5.7 |
1.2 (1.0–1.5) 0.049 |
14.8 (11.1–19.7) <0.0001 |
18.1 (14.4–22.7) <0.0001 |
*
Bold P-values significant (P<0.05) by logistic regression.
HC: Healthy Controls.
NC: Not calculable due to 0 value.