Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Jul 24;8:106. doi: 10.1038/s41467-017-00127-0

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 6 — Calcium current in PKP2-cKO cardiomyocytes at 21 dpi. a L-type calcium current in control (black) and PKP2-cKO (red). b Peak L-type calcium current density as a function of voltage recorded in control (black) and PKP2-cKO (red) cardiomyocytes. Voltage clamp protocol in inset. c Normalized L-type calcium current decay in control (black) and PKP2-cKO (red) cardiomyocytes. Inset: Tau of inactivation of the L-type calcium current in control (black) and PKP2-cKO (red) cardiomyocytes. Student’s t-test, *p < 0.05 vs. control. d L-type calcium current decay in control (black) and PKP2-cKO (red) cardiomyocytes. Inset: Charge (Q) passing through calcium channels during L-type calcium current in control (black) and PKP2cKO (red) cardiomyocytes. For b, c and d, results collected from 13 cells, three mice in the control group and 10 cells, three mice in the PKP2-cKO group. e Example of SICM recording showing crest and T-tubules. f Occurrence ratio of calcium channels at crest and T-tubules measured by SICM in control (n = 11 and 18 for crest and T-tubules respectively; black) and PKP2-cKO (n = 15 and 22 for crest and T-tubules respectively; red) cardiomyocytes. Five mice in each group. χ ² test, *p < 0.05 vs. control. g Calcium channel unitary conductance in control (n = 5; black) and PKP2-cKO (n = 5; red) cardiomyocytes. Five mice in each group