Table 1.
Synthesis of target compounds (5a–5n)
| Entry | Target compounds | Method-1 (diamine + cinnamic acid) | Method-2 (2-MeBz + aldehydes) | m.p (°C) | ||||
|---|---|---|---|---|---|---|---|---|
| Time (h) | Temp (°C) | Yield (%) | Time (h) | Temp (°C) | Yield (%) | |||
| 5a |
|
5 | 160 | 74 | 6 | 160 | 75 | 202–204 |
| 5b |
|
5 | 160 | 68 | 6 | 160 | 70 | 178–180 |
| 5c |
|
5 | 160 | 80 | 6 | 160 | 76 | 130–132 |
| 5d |
|
5 | 150 | 73 | 6 | 160 | 76 | 210–212 |
| 5e |
|
5 | 150 | 78 | 6 | 160 | 76 | 198–200 |
| 5f |
|
5 | 160 | 74 | 5 | 160 | 76 | >240 |
| 5g |
|
5 | 160 | 68 | 5 | 150 | 66 | 100–102 |
| 5h |
|
5 | 150 | 78 | 5 | 150 | 74 | 108–110 |
| 5i |
|
5 | 160 | 75 | 5 | 150 | 75 | >220 |
| 5j |
|
5 | 150 | 76 | 6 | 160 | 74 | 200–220 |
| 5k |
|
6 | 160 | 75 | 5 | 150 | 75 | 190–210 |
| 5l |
|
5 | 150 | 75 | 6 | 160 | 74 | 202–204 |
| 5m |
|
5 | 160 | 74 | 5 | 150 | 75 | 205–210 |
| 5n |
|
6 | 150 | 75 | 6 | 160 | 75 | 210–220 |