Figure 1.
Laser ablation-inductively coupled plasma-mass spectrometry (LA–ICP–MS) is used to reveal and quantify metals in brain tissue. To show the microspatial distribution of vanadium metal within anatomical regions of mice brain after chronic exposure. BASAL INDICES: 80 μm × 80 μm square laser spot, 3% laser power with 0.4 J/cm2 confluence, 320 μm/s laser speed, 20 Hz, 0.25 s Integration. (A–D, control brains), (E–H, vanadium exposed brains), (I–K, withdrawal brains) at 3, 6, 15 and 18 months time points of treatments.