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GLUT5 transport kinetics and inhibition in hxt 0 yeast cells (see also Fig. 4).
| GLUT5 variant | KM [mM] | IC50 of MSNBA [µM] | IC50 of ECG [µM] |
|---|---|---|---|
| S72Y | 10.8 ± 1.0 | 26.6 ± 6.7 | 180 ± 11 |
| S76I | 14.6 ± 1.1 | 6.3 ± 0.7 | 140 ± 11 |
| WT in MCF-7 cells or in X. laevis oocytes* | ~1017* | 5.8 ± 0.520* | Ki = 117 ± 5418* |
*Values from References indicated in superscript.
