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. 2017 Jul 24;7:6300. doi: 10.1038/s41598-017-06684-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Sustained efficacy of the seizure suppression during the four-month long stimulation. (a and b) Results of an extended 4 months long treatment are similar to those obtained during the 6 weeks protocol (Fig. 4b and c), both for the Time in Seizure (a) and average seizure duration (b). Shaded area represents ± SD. (Control period at the end of the 6 week treatment is removed).