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. 2017 Jul 24;7:6219. doi: 10.1038/s41598-017-06676-0

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Model of the dynamic nuclear organization of GR. Schematic representation of GR dynamic partition within the nuclear landscape. GR diffusing molecules engage in shorter-lived and longer-lived interactions with chromatin targets (I), DNA-dependent foci (II) or NCoA-2 bodies (III). To simplify the scheme, the cartoon does not include the oligomeric state of GR.