Table 1.
Glycosylation of DENV proteins.
| Serotypes∗ | DENV 1 | DENV 2 | DENV 3 | DENV 4 |
|---|---|---|---|---|
| C | NA | NA | NA | NA |
| PrM± | N64-69 | |||
| E | N67 and N153 | N67 and N153 | N67 and N153 | N67 and N153 |
| NS1 | N130 and N207 | N130 and N207 | N130 and N207 | N130 and N207 |
| NS2A | Va | Va | Va | Va |
| NS2B | NA | NA | NA | NA |
| NS3 | Va | Va | Va | Va |
| NS4A | Va | Va | Va | Va |
| NS4B | Va | Va | Va | Va |
| NS5 | Va | Va | Va | Va |
NA, not applicable (NxT/S motif is not identified).
Va, the presence and number of NxT/S motifs vary among serotypes.
∗DENV 1 strain Nauru/West Pac/1974 (Accession no:U88535) or strain 45AZ5 (Accession no: NC_001477), DENV 2 strain SG/D2Y98P-PP1/2009 (Accession no: JF327392), DENV 3 strain GZ/10476/2012 (Accession no: KC261634) and DENV 4 isolate GZ30 (Accession no: JQ822247) are aligned against protein entries from Conserved Domain Database (CDD) or UniProt using BLAST (Basic Local Alignment Search Tool).
±The N-glycosylation site is located at residue 64 to 69 depending on the serotype.