Table 1.
Frequency of APOE genotype by LIPGENE Dietary Fatty Acid Intervention Study center (n = 442).
| All | Norway | Sweden | Ireland | Netherlands | UK | Poland | France | Spain | |
|---|---|---|---|---|---|---|---|---|---|
| Genotype (n, %) | |||||||||
| E2/E2 | 3 (0.7) | 0 (0.0) | 0 (0.0) | 0 (0.0) | 1 (2.2) | 1 (1.7) | 0 (0.0) | 0 (0.0) | 1 (1.4) |
| E2/E3 | 43 (9.7) | 5 (8.7) | 4 (8.3) | 7 (12.0) | 7 (15.9) | 5 (8.6) | 7 (10.3) | 2 (5.1) | 6 (8.5) |
| E2/E4 | 17 (3.8) | 3 (5.2) | 3 (6.2) | 1 (1.7) | 1 (2.2) | 2 (3.4) | 2 (2.9) | 2 (5.1) | 3 (4.2) |
| E3/E3 | 264 (59.7) | 27 (47.3) | 26 (54.1) | 37 (63.8) | 26 (59.0) | 26 (44.8) | 42 (61.8) | 28 (71.8) | 52 (74.2) |
| E3/E4 | 103 (23.3) | 21 (36.8) | 15 (31.2) | 10 (17.2) | 7 (15.9) | 21 (36.2) | 16 (23.5) | 6 (15.3) | 7 (10.0) |
| E4/E4 | 12 (2.7) | 1 (1.7) | 0 (0.0) | 3 (5.1) | 2 (4.5) | 3 (5.1) | 1 (1.4) | 1 (2.5) | 1 (1.4) |
| E2 carriersa | 46 (10.4) | 5 (8.7) | 4 (8.3) | 7 (12.0) | 8 (18.1) | 6 (10.3) | 7 (10.2) | 2 (5.1) | 7 (10.0) |
| E4 carriersb | 115 (26.0) | 22 (38.6) | 15 (31.2) | 13 (22.4) | 9 (20.4) | 24 (41.3) | 17 (24.9) | 7 (17.9) | 8 (11.4) |
| ALL | 442 | 57 | 48 | 58 | 44 | 58 | 68 | 39 | 70 |
| Allele frequency (%) | |||||||||
| ε2 | 7.5 | 7.0 | 7.3 | 6.9 | 11.4 | 7.8 | 6.6 | 6.3 | 7.9 |
| ε3 | 76.2 | 70.2 | 74.0 | 78.4 | 75.0 | 67.2 | 78.8 | 81.3 | 83.6 |
| ε4 | 16.3 | 22.8 | 18.8 | 14.7 | 13.6 | 25.0 | 14.7 | 12.6 | 8.6 |
Values are n (%). aGenotype groups combined; E2 carriers represent E2/E2 and E2/E3. bGenotype groups combined; E4 carriers represent E4/3 and E4/E4.