. 2017 Jun 30;12(4):387–399. doi: 10.1007/s11523-017-0508-3

Table 1.

Markers used to identify normal stem cells and CSCs [10, 34, 35]

ALDH⁺, ALDH1^high, α2β1 ^high, A2B5 ⁺, ABCG2^high

BCRP1⁺, BMI1⁺

CD15, CD20⁺, CD24⁺, CD24^−/low, CD29, CD34, CD38⁻, CD44⁺, CD49f⁺, CD71⁻, CD90⁻, CD117⁻, CD123⁺, CD133⁺, CD138⁻, CD166⁺, CEA⁺, CK20⁺, CXCR4⁺

ESA⁺, EpCAM⁺

HLA-DR⁻

Lineage⁻, LGR5⁺

NANOG

OCT4

SOX2, SSEA⁺

YAP1⁺

− negative; + positive; ALDH aldehyde dehydrogenases; BCRP1 breakpoint cluster region pseudogene 1; BMI1 B-cell-specific Moloney murine leukemia virus integration site 1; CEA carcinoembryonic antigen; CK20 cytokeratin 20; CXCR4 C-X-C chemokine receptor type 4; ESA epithelial-specific antigen; EpCAM epithelial cell adhesion molecule; HLA-DR human leukocyte antigen–antigen D related; LGR5 leucine-rich repeat-containing G-protein coupled receptor 5; OCT4 organic cation/carnitine transporter 4; SOX2 sex determining region Y-box 2; SSEA stage-specific embryonic antigen; YAP1; yes-associated protein 1