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. 2017 Jul 24;7:6250. doi: 10.1038/s41598-017-06570-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Genipin crosslinking influences the morphological and mechanical properties of fibrin scaffolds. (A) The effect of genipin concentration on fiber diameter (biological n = 3, technical n = 10). (B) The effect of genipin concentration on pore size of fibrin scaffolds (biological n = 3, technical n = 30). (C) The effect of genipin on elastic modulus. The elastic modulus for spinal cord tissue is taken from³⁷. Each group is represented by its mean average with error bars indicating the S.E.M. *Indicates p < 0.05 compared to control (0 mM).