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. 2017 Jul 24;7:6238. doi: 10.1038/s41598-017-06217-9

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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HLJDT-M, but not HLJDT, reduces hippocampal Aβ-plaque pathology in 3XTg-AD mice. Immunohitochemical labelling of Aβ with 4G8 antibody in representative figures taken from the coronal sections in 3XTg-AD mice were orally administered with HLJDT-M or HLJDT at doses of 1 and 2 g/kg per day for 6 months.