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. 2017 Jul 19;8:15878. doi: 10.1038/ncomms15878

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Copyright © 2017, The Author(s)

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/

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(a) Representative mEPSC traces from recordings of putative OLM neurons in the stratum oriens of hippocampal slices from WT and TRPV1 knockouts. (b) Quantitation of mEPSC frequency, and amplitude (c) in WT and TRPV1 knockout OLM neurons (WT n=19 neurons, TRPV1 KO n=16; error=s.e.m., significance determined by unpaired Student’s t-test with Welch’s correction, *P<0.05). (d) Current responses to perfusion of 1 μM capsaicin in recorded putative OLM neurons in WT and TRPV1 knockout (e) hippocampal slices (WT n=12 neurons, TRPV1 KO n=19).