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. 2017 Jul 19;8:16065. doi: 10.1038/ncomms16065

Figure 5. Disulfide isomerase range of motion.

Figure 5

Top and side views of (a) U-shaped human PDI with two catalytic domains (PDB: 4EKZ and 4EL1), (b) V-shaped homodimeric EcDsbC with two catalytic domains (PDB: 1JZD and 1EEJ) and (c) homotrimeric PmScsC (this work, PDB: 4XVW and 5ID4) showing its expansive twisting and elongation motions. Catalytic domains are shown in green, active sites (CXXC) in orange, and oligomerization or non-catalytic domains in white. See also Supplementary Movie 1.