Table 3.
Percentage differences in cortical and trabecular vBMD and total hip aBMDat 60–64 years per 1 SD increase in the cognitive scores at age 15 and 53, adjusted for body size and additionally adjusted for height tempo, adult health behaviors and later (at age 53) and prior cognition (at age 15), respectively.
pQCT Measures | DXA Measures | ||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
pQCT- 50% radius (mg/cm3) | pQCT-4% radius (mg/cm3) | DXA aBMD (g/cm2) | |||||||||||
Cortical vBMD (mg/cm3) | Trabecular vBMD (mg/cm3) | Total Hip aBMD | |||||||||||
N | % | 95% CI | p | N | % | 95% CI | p | N | % | 95% CI | p | ||
WOMEN | |||||||||||||
Cognition 15 | |||||||||||||
Additionally adjusted for SITAR height-tempo | 577 | 0.1 | −0.2 to 0.4 | 0.56 | 569 | −0.8 | −2.9 to 1.3 | 0.43 | 702 | 1 | 0 to 2 | 0.04 | |
Additionally adjusted for Occupational class, smoking and physical activity | 577 | 0.01 | −0.3 to 0.3 | 0.96 | 569 | −1 | −3.2 to 1.2 | 0.37 | 702 | 0.8 | −0.3 to 1.8 | 0.15 | |
Additionally adjusted for Memory at age 53 | 577 | 0.01 | −0.3 to 0.3 | 0.90 | 569 | −0.8 | −3 to 1.4 | 0.48 | 702 | 0.8 | −0.2 to 1.8 | 0.12 | |
MEN | |||||||||||||
Cognition 15 | |||||||||||||
Additionally adjusted for SITAR height-tempo | 527 | 0.6 | 0.3 to 0.8 | <0.001 | 524 | 1.5 | −0.4 to 3.4 | 0.12 | 625 | 0.3 | 0.7 to 1.3 | 0.56 | |
Additionally adjusted for Occupational class, smoking and physical activity | 527 | 0.5 | 0.2 to 0.8 | 0.001 | 524 | 0.9 | −1.3 to 3.1 | 0.43 | 625 | 0.7 | −0.5 to 1.9 | 0.23 | |
Additionally adjusted for Memory at age 53 | 527 | 0.5 | 0.2 to 0.8 | 0.002 | 524 | 0.7 | −1.5 to 2.9 | 0.54 | 625 | 0.7 | −0.5 to 1.9 | 0.27 | |
Search speed at age 53 | |||||||||||||
Additionally adjusted for SITAR height-tempo | 527 | 0.2 | −0.1 to 0.4 | 0.2 | 524 | 2.1 | 0.2 to 4 | 0.02 | 625 | 0.4 | −0.6 to 1.5 | 0.39 | |
Additionally adjusted for Occupational class, smoking and physical activity | 527 | 0.01 | −0.2 to 0.3 | 0.75 | 524 | 1.4 | −0.5 to 3.4 | 0.13 | 625 | 0.4 | −0.6 to 1.5 | 0.40 | |
Additionally adjusted for Cognition 15 | 527 | 0.01 | −0.3 to 0.3 | 0.92 | 524 | 1.4 | −0.6 to 3.3 | 0.16 | 625 | 0.4 | −0.7 to 1.4 | 0.47 |