Table 1.
Purpose | Treatment | Number of rats |
---|---|---|
Pharmacological safety | Vehicle | 4 |
Ax-C-8 (5 mg/day) | 4 | |
Ax-C-8 (25 mg/day) | 4 | |
Ax-C-8 (49 mg/day) | 9 | |
Antioxidant property against acute renal oxidative injury in basal diet (Ax-C-8; 0.02%, w/w) | Vehicle | 4 |
Vehicle + Fe-NTA 1 h | 5 | |
Ax-C-8 + Fe-NTA 1 h | 5 | |
Vehicle + Fe-NTA 4 h | 5 | |
Ax-C-8 + Fe-NTA 4 h | 6 | |
Vehicle + Fe-NTA 24 h | 6 | |
Ax-C-8 + Fe-NTA 24 h | 6 | |
Antioxidant property against subacute renal oxidative injury in Vitamin E-deficient diet | Vehicle | 4 |
Vehicle + Fe-NTA | 6 | |
Ax-C-8 (0.01%) + Fe-NTA | 6 | |
Ax-C-8 (0.02%) + Fe-NTA | 6 | |
Ax-C-8 (0.04%) + Fe-NTA | 6 |