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Effect of caloric restriction and DNJ on colon tissue in male mice with induced colorectal cancer. (A) Colon tissue in each group. Arrows indicate tumors. (B) Representative histology images from hematoxylin and eosin-stained colon specimens (magnification ×4): (I) normal colon, (II) colon tissue with mild pathology, (III) dysplastic crypts, and (IV) well-differentiated tubular adenocarcinoma. Bars indicate 100 µm.
