Table 1.
Effect of calorie restriction and DNJ on growth parameters in colon cancer-induced male mice
| CO− | CO+ | CR | L-DNJ | H-DNJ | |
|---|---|---|---|---|---|
| Food intake (g/day) | 5.41 ± 0.04b | 5.69 ± 0.08b,c | 4.45 ± 0.07a | 5.66 ± 0.09b,c | 5.72 ± 0.08c |
| Energy intake (kcal/day) | 18.7 ± 0.15b | 19.6 ± 0.28b,c | 15.4 ± 0.20a | 19.5 ± 0.31b,c | 19.7 ± 0.27c |
| Final body weight (g) | 44.5 ± 0.91 | 43.8 ± 0.79 | 41.4 ± 0.32 | 43.0 ± 0.39 | 41.7 ± 0.67 |
| Tissue weight (g/100 g body weight) | |||||
| Liver | 4.09 ± 0.06 | 4.49 ± 0.13 | 4.33 ± 0.15 | 4.47 ± 0.09 | 4.38 ± 0.13 |
| Pancreas | 0.85 ± 0.03 | 0.93 ± 0.04 | 0.90 ± 0.04 | 0.93 ± 0.04 | 0.92 ± 0.04 |
| Kidney | 1.82 ± 0.03a | 1.92 ± 0.05a,b | 1.90 ± 0.04a,b | 2.03 ± 0.04b | 1.89 ± 0.06a,b |
| Epididymis adipose | 1.46 ± 0.18a | 1.09 ± 0.12a,b | 0.79 ± 0.12b | 0.80 ± 0.11b | 0.77 ± 0.13b |
Values are means ± SE, n = 18–20. Means in a row with different letters are significantly different at p<0.05.