. 2017 May 16;61(1):47–52. doi: 10.3164/jcbn.16-94

Table 2.

Effect of calorie restriction and DNJ on plasma, liver and colon parameters in colon cancer-induced male mice

	CO−	CO+	CR	L-DNJ	H-DNJ
Serum
Triacylglycerol (mmol/L)	1.51 ± 0.09	1.57 ± 0.09	1.50 ± 0.10	1.72 ± 0.14	1.45 ± 0.11
Total cholesterol (mmol/L)	2.32 ± 0.06^a^,^b	2.19 ± 0.04^a	2.11 ± 0.06^a	2.55 ± 0.08^b	2.23 ± 0.07^a
Phospholipid (mmol/L)	2.24 ± 0.04^a	2.15 ± 0.05^a	2.14 ± 0.07^a	2.51 ± 0.09^b	2.24 ± 0.08^a
Glucose (mmol/L)	4.57 ± 0.20	5.03 ± 0.26	5.00 ± 0.18	4.69 ± 0.21	5.04 ± 0.28
Insulin (mg/L)	0.24 ± 0.03^a^,^b	0.26 ± 0.04^a	0.15 ± 0.03^b	0.15 ± 0.01^b	0.15 ± 0.01^b
HOMA-IR	1.00 ± 0.15	1.20 ± 0.20	0.66 ± 0.06	0.65 ± 0.06	0.66 ± 0.07
TBARS (µmol/L)	5.14 ± 0.21^a	5.47 ± 0.48^a	4.17 ± 0.23^b	4.90 ± 0.29^a^,^b	4.27 ± 0.25^b
ALT (UI/L)	9.75 ± 0.42	10.4 ± 0.52	10.0 ± 0.54	9.50 ± 0.92	11.5 ± 0.57
AST (UI/L)	53.0 ± 5.44^a	61.0 ± 7.89^b	46.5 ± 5.28^a	44.7 ± 3.32^a	43.5 ± 2.41^a
Liver
Triacylglycerol (µmol/g)	12.2 ± 1.13	8.82 ± 0.84	11.0 ± 1.21	13.0 ± 1.34	10.7 ± 1.39
Total cholesterol (µmol/g)	7.68 ± 0.65	7.84 ± 0.73	7.02 ± 0.20	6.45 ± 0.50	6.55 ± 0.41
Phospholipid (µmol/g)	34.5 ± 0.8	32.7 ± 1.4	35.4 ± 1.0	35.5 ± 1.2	34.6 ± 1.4
TBARS (nmol/g)	68.9 ± 5.3^a	63.6 ± 3.9^a	44.7 ± 2.8^b	59.5 ± 3.1^a	41.1 ± 3.3^b
Colon
TBARS (nmol/g)	8.6 ± 0.7^a	21.2 ± 1.3^c	14.9 ± 0.9^b	18.8 ± 1.0^c	13.7 ± 1.1^b

Values are means ± SE, n = 18–20. Means in a row with different letters are significantly different at p<0.05. HOMA-IR, homeostasis model assessment-insulin resistance; TBARS, thiobarbituric acid reactive substances; ALT, alanine transaminase; AST, aspartate aminotransferase.