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. Author manuscript; available in PMC: 2017 Dec 1.
Published in final edited form as: Cancer Immunol Res. 2017 May 4;5(6):439–445. doi: 10.1158/2326-6066.CIR-16-0364

Figure 1. Addition of agonistic anti-4-1BB antibody allows for the generation of CD8+ TILs from TNBC tumor fragments.

Figure 1

(A) The total number of TILs expanded from 7 TNBC patients, reported as per single-fragment growth, because diverse number of fragments were put in culture depending on the tumor sample size obtained post-surgery. The absolute number is shown as determined by trypan blue exclusion. Growth per patient (left) and per culture condition (right) is shown. (B) The percentage of CD8+ TILs (left) and CD4+ TILs (right) obtained after 28 days of culture with IL2 alone or with IL2 + anti-4-1BB from 6 independent lines.