Table 1.
Case | Prior treatments | Age | Subtype | cStage | pStage | Grade | Method of isolation | Total number of TIL (IL-2) 106 | Total number of TIL (IL-2 + 4-1BB) 106 | TIL/fragment (IL-2) 106 | TIL/fragment (IL-2 + 4-1BB) 106 | Number of fragment (IL-2) | Number of fragment (IL-2 + 4-1BB) |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Panitsumab, Abraxane, Carboplatin, FAC | 52 | IBC-TNBC | cT4dN3bM0 IIIc | ypT4bN3b | 2 | Enzymatic digestion | * NA | NA | ** NG | NG | NA | NA |
2 | PTX, FAC | 63 | IBC-TNBC | cT4dNxM1 IV | ypT1miN2a | 3 | Enzymatic digestion Mechanical disruption |
NA | NA | NG | NG | NA | NA |
3 | Capecitabine | 76 | IBC-TNBC | cT4dN2M0 IIIB | ypT4dN3 | 2 | Fragment | NA | NA | NG | NG | NA | NA |
4 | none | 71 | TNBC | cT1cN0M0 IA | ypT1aN0 | 2 | Fragment | 20.8 | 34.3 | 3.5 | 11.4 | 6 | 3 |
5 | Abraxane, FAC | 55 | TNBC | cT2N0M0 IIA | ypT1aN0 | 3 | Fragment | 16.6 | 34.6 | 4.2 | 17.3 | 4 | 2 |
6 | PTX, FAC | 57 | IBC-TNBC | cT4dN2M0 IIIB | ypT0N0 | 3 | Fragment | 16.9 | 520.3 | 1.2 | 37.2 | 14 | 14 |
7 | PTX, FAC | 34 | TNBC | cT2N1M0 IIB | ypT1cN1 | 3 | Fragment | 30.8 | 519.3 | 3.8 | 64.9 | 8 | 8 |
8 | PTX, FAC | 51 | TNBC | cT2N0M0 IIA | ypT1cN0 | 3 | Fragment | 111.1 | 160.1 | 9.3 | 13.3 | 12 | 12 |
9 | PTX, FAC | 79 | TNBC | cT3N1M0 IIIA | ypT2N0 | 3 | Fragment | 0.00629 | 5.8 | 0.000524 | 0.481 | 12 | 12 |
NA = None Available
NG = No Growth