Table 2.

Simulation results

	First stage		Simulations in which arm was dropped at interimc	Assumed
Study arm	aProportion	SDb	Proportion	Proportiond
1 Standard of care	0.250	0.048	NA	0.250
2 Intervention	0.291	0.055	0.441	0.290
3 Intervention	0.299	0.058	0.336	0.300
4 Intervention	0.310	0.059	0.215	0.310
5 Intervention	0.321	0.061	0.114	0.320
6 Intervention	0.400	0.078	0.000	0.400

Exact intervention not specified here as there is no evidence about a particular one of the 5 interventions being investigated

SD standard deviation

^aProportion of male partners linked to care or prevention

^bAssumed (0.050, 0.058, 0.060, 0.062, 0.064, 0.080) in arms 1–6, respectively

^cScenarios assumed for the 6 trial arms at the start

^dIf p value was > 0.2 at interim analysis, discontinued from recruitment