Skip to main content
. 2017 Jul 24;18:70. doi: 10.1186/s12863-017-0533-3

Table 1.

Comparison of methods given fixed sample size and increasing number of null SNPs, α=0.01

Model 0 Null SNPs 45 Null SNPs 300 Null SNPs 900 Null SNPs 20,000 Null SNPs
Lasso-PL 0.840 0.831 (0.008) 0.841 (0.0081) 0.857 (0.0083) 0.841 (0.0095)
Lasso-AL 0.850 0.850 (0.0102) 0.851 (0.0089) 0.854 (0.0077) 0.828 (0.0079)
Lasso-Ayers 0.819 0.808 (0.0121) 0.836 (0.0096) 0.846 (0.0086) 0.838 (0.0095)
SMA 0.828 0.828 (0.0106) 0.828 (0.0101) 0.828 (0.01) 0.828 (0.01)
Lasso-PT 0.829 0.832 (0.0078) 0.827 (0.0073) 0.818 (0.0076) 0.560 (0.0013)
Lasso-RB 0.869 0.859 (0.0137) 0.847 (0.0106) 0.833 (0.0089) 0.555 (0.0012)
Lasso-MRB(t=0.001) 0.869 0.865 (0.0138) 0.850 (0.0105) 0.838 (0.0089) 0.556 (0.0012)
Lasso-MRB(t=0.005) 0.869 0.863 (0.0137) 0.849 (0.0105) 0.836 (0.009) 0.555 (0.0012)
Lasso-MRB(t=0.01) 0.869 0.864 (0.0139) 0.849 (0.0105) 0.837 (0.009) 0.556 (0.0012)
Lasso-MRB(t=0.03) 0.869 0.864 (0.0136) 0.849 (0.0102) 0.839 (0.0092) 0.558 (0.0013)
Lasso-MRB(t=0.05) 0.869 0.859 (0.0124) 0.841 (0.0099) 0.833 (0.0089) 0.559 (0.0013)

Models are compared by their true positive rate and false positive rate (in parentheses), across 300 simulated datasets, using a significance level of α=0.01. Each column represents a scenario where a different number of null SNPs were used (e.g. 0, 45, 300, 900, or 20,000)