Table 1.
Model | 0 Null SNPs | 45 Null SNPs | 300 Null SNPs | 900 Null SNPs | 20,000 Null SNPs |
---|---|---|---|---|---|
Lasso-PL | 0.840 | 0.831 (0.008) | 0.841 (0.0081) | 0.857 (0.0083) | 0.841 (0.0095) |
Lasso-AL | 0.850 | 0.850 (0.0102) | 0.851 (0.0089) | 0.854 (0.0077) | 0.828 (0.0079) |
Lasso-Ayers | 0.819 | 0.808 (0.0121) | 0.836 (0.0096) | 0.846 (0.0086) | 0.838 (0.0095) |
SMA | 0.828 | 0.828 (0.0106) | 0.828 (0.0101) | 0.828 (0.01) | 0.828 (0.01) |
Lasso-PT | 0.829 | 0.832 (0.0078) | 0.827 (0.0073) | 0.818 (0.0076) | 0.560 (0.0013) |
Lasso-RB | 0.869 | 0.859 (0.0137) | 0.847 (0.0106) | 0.833 (0.0089) | 0.555 (0.0012) |
Lasso-MRB(t=0.001) | 0.869 | 0.865 (0.0138) | 0.850 (0.0105) | 0.838 (0.0089) | 0.556 (0.0012) |
Lasso-MRB(t=0.005) | 0.869 | 0.863 (0.0137) | 0.849 (0.0105) | 0.836 (0.009) | 0.555 (0.0012) |
Lasso-MRB(t=0.01) | 0.869 | 0.864 (0.0139) | 0.849 (0.0105) | 0.837 (0.009) | 0.556 (0.0012) |
Lasso-MRB(t=0.03) | 0.869 | 0.864 (0.0136) | 0.849 (0.0102) | 0.839 (0.0092) | 0.558 (0.0013) |
Lasso-MRB(t=0.05) | 0.869 | 0.859 (0.0124) | 0.841 (0.0099) | 0.833 (0.0089) | 0.559 (0.0013) |
Models are compared by their true positive rate and false positive rate (in parentheses), across 300 simulated datasets, using a significance level of α=0.01. Each column represents a scenario where a different number of null SNPs were used (e.g. 0, 45, 300, 900, or 20,000)