Table 2.
Estimate effect of cupping therapy and acupuncture for pain-related conditions
| Study ID | Sample size | Disease | Estimate effect | P | Outcomes |
|---|---|---|---|---|---|
| Zhou [19] | 200 | Cervical spondylosis | MD −1.70, 95% CI −1.94 to −1.46 | P < 0.00,001 | VAS for pain |
| Mou [21] | 124 | Cervical spondylotic radiculopathy | MD 0.11, 95% CI −0.78 to 1.00 MD 4.33, 95% CI −3.14 to 11.80 MD 1.59, 95% CI −1.17 to 4.35 |
P = 0.81 P = 0.26 P = 0.26 |
VAS Neck disability index (physical therapy) CAS |
| Wang [25] | 80 | Knee osteoarthritis | RR 1.29, 95% CI 0.32 to 5.19 RD 0.03, 95% CI −0.11 to 0.16 |
P = 0.72 P = 0.72 |
Symptom improvement rate |
| Wang [26] | 171 | Knee osteoarthritis | MD −0.97, 95% CI −1.56 to −0.38 MD −1.35, 95% CI −1.91 to −0.79 MD −1.01, 95% CI −1.87 to −0.15 MD −0.17, 95% CI −0.52 to 0.18 MD −2.92, 95% CI −6.18 to 0,34 MD −4.14, 95% CI −8.49 to 0.21 MD −1.66, 95% CI −2.48 to −0.84 MD −0.35, 95% CI −0.68 to −0.02 MD −4.93, 95% CI −7.97 to −1.89 MD −6.93, 95% CI −11.0 to −12.85 |
P = 0.001 P < 0.00001 P = 0.02 P = 0.34 P = 0.08 P = 0.06 P < 0.0001 P = 0.04 P = 0.001 P = 0.0009 |
VAS VAS (follow at 4 weeks) WOMAC—pain scores WOMAC—stiff scores WOMAC—difficult of life scores WOMAC —total scores WOMAC—pain scores (follow at 4 weeks) WOMAC—stiff scores (follow at 4 weeks) WOMAC—difficult of life scores (follow at 4 weeks) WOMAC total scores (follow at 4 weeks) |
| Wang [29] | 62 | Lumber disk herniation | MD 1.88, 95% CI −0.24 to 4.00 RR 0.89, 95% CI 0.63 to 1.27 RD −0.07, 95% CI −0.31 to 0.16 |
P = 0.08 P = 0.53 P = 0.53 |
JOA scores Symptom improvement rate |
| Zhou [30] | 120 | The third lumber vertebral transverse process syndrome | RR 1.05, 95% CI 0.96 to 1.15 RD 0.05, 95% CI −0.03 to 0.13 MD −1.58,95% CI −2.04 to −1.12 |
P = 0.25 P = 0.24 P < 0.00001 |
Symptom improvement rate VAS scores |
| Zhang [31] | 40 | Postherpetic neuralgia | RR 0.95, 95% CI 0.83 to 1.09 RD −0.05, 95% CI −0.18 to 0.08 MD 0.10, 95% CI −0.51 to 0.70 |
P = 0.47 P = 0.44 P = 0.75 |
Symptom improvement rate VAS |
| Huang [32] | 96 | Postherpetic neuralgia | RR 1.16, 95% CI 1.00 to 1.33 RD 0.13, 95% CI 0.01 to 0.25 MD −1.17, 95% CI −1.67 to −0.67 |
P = 0.05 P = 0.04 P < 0.00001 |
Symptom improvement rate VAS |
| Wu [33] | 407 | Toothache | RR 1.04, 95% CI 1.00 to 1.08 RD 0.03, 95% CI 0.00 to 0.07 |
P = 0.03 P = 0.03 |
Symptom improvement rate |
| Liu [36] | 76 | Muscles fibrositis | RR 1.05, 95% CI 0.96 to 1.15 RD 0.05, 95% CI −0.03 to 0.14 |
P = 0.24 P = 0.22 |
Symptom improvement rate |
| Huang [37] | 264 | Soft tissue contusion | RR 0.99, 95% CI 0.93 to 1.05 RD −0.01, 95% CI −0.06 to 0.05 |
P = 0.79 P = 0.79 |
Symptom improvement rate |
| Zhou [38] | 46 | Acute lumbar sprain | RR 1.09, 95% CI 0.90 to 1.33 RD 0.08, 95% CI −0.10 to 0.25 |
P = 0.39 P = 0.38 |
Symptom improvement rate |
| Wang [39] | 120 | Acute ankle joint | RR 1.18, 95% CI 1.04 to 1.33 RD 0.15, 95% CI 0.04 to 0.25 |
P = 0.009 P = 0.005 |
Symptom improvement rate |
| Cao [40] | 56 | Fibromyalgia | MD −4.06, 95% CI −5.4 to 13.72 MD −5.93, 95% CI −7.89 to 19.75 MD −0.42, 95% CI −4.09 to 4.93 |
VAS Quality of life HAMD |
VAS Visual Analogue Scale, MD mean difference, CAS the Clinical Assessment Scale, WOMAC the Western Ontario and McMaster Universities osteoarthritis index, JOA the Joint Operational Area, SF-36 the MOS item short from health survey, HAMD the Hamilton Depression Scale