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Schematic representation of Trpm2 isoforms. Wild-type (WT) transient receptor potential melastatin 2 (Trpm2) is also known as Trpm2-L. Membrane spanning domains 1–4 and the putative pore region including transmembrane domains 5–6 are indicated. CCR represents the coiled-coil region which may mediate protein/protein interactions. NUDT9-H represents the NUDT9 adenosine diphosphate–ribose hydrolase (also known as NUDIX) domain.
