Table 4.
AA Cases (n=51) |
AA Controls (n=51) |
AA Cases vs AA Controls | NHW Cases (n=28) |
NHW Controls (n=28) |
NHW Cases vs NHW Controls | AA Cases vs NHW Cases | AA Controls vs NHW Controls | |
---|---|---|---|---|---|---|---|---|
Demographics and Anthropometrics | Median (IQ) | Median (IQ) | a p-value | Median (IQ) | Median (IQ) | a p-value | b p-value | b p-value |
BMI (kg/m2) | 27(7) | 27(7) | 0.45 | 28(5) | 28(5) | 0.59 | 0.40 | 0.27 |
WC (cm)c | 99(14) | 106(19) | 0.16 | 104(23) | 111(17) | 0.41 | 0.08 | 0.03* |
Abdominal Depots | ||||||||
TAT (cm2) | 263(264) | 320(288) | 0.45 | 366(253) | 369(239) | 0.46 | 0.05* | 0.02* |
SAT (cm2) | 127(72) | 165(146) | 0.02* | 144(101) | 185(107) | 0.71 | 0.25 | 0.18 |
SSAT (cm2)c | 88(40) | 111(68) | <0.01* | 88(41) | 112(50) | 0.09 | 0.85 | 0.54 |
DSAT (cm2) | 62(50) | 71(72) | 0.06 | 77(65) | 96(73) | 0.39 | 0.10 | 0.06 |
VAT (cm2) | 98(178) | 114(168) | 0.47 | 190(162) | 180(167) | 0.42 | 0.06 | <0.01* |
SM (cm2) | 172(39) | 178(33) | 0.30 | 150(31) | 172(46) | 0.20 | <0.01* | 0.18 |
VAT/TAT (%) | 42(25) | 34(25) | 0.01* | 47(21) | 48(17) | 0.58 | 0.28 | <0.01* |
VAT/SAT (%) | 81(89) | 55(65) | 0.01* | 99(84) | 103(75) | 0.97 | 0.25 | <0.01* |
SAT/TAT (%) | 52(21) | 61(20) | <0.01* | 47(20) | 46(18) | 0.78 | 0.24 | <0.01* |
SSAT/TAT (%)c | 35(23) | 43(25) | 0.20 | 34(20) | 30(8) | 0.58 | 0.13 | <0.01* |
DSAT/TAT (%) | 24(13) | 30(12) | 0.01* | 25(12) | 25(12) | 0.18 | 0.95 | 0.03* |
Weight Stable Sub-Groupd | ||||||||
WC (cm2) | 104.6(16) | 109(23) | 0.96 | 106(21) | 111(13) | 0.28 | 0.63 | 0.25 |
SSAT (cm2) | 96(37) | 123(76) | 0.05 | 91(38) | 124(47) | 0.07 | 0.26 | 0.80 |
DSAT (cm2) | 78(42) | 86(76) | 0.32 | 88(63) | 91(68) | 0.47 | 0.53 | 0.53 |
VAT (cm2) | 170(148) | 138(147) | 0.07 | 172(181) | 186(163) | 0.18 | 0.83 | 0.04* |
Significant p-value <0.05.
Paired t-test used for comparisons between cases and controls for continuous data.
Dependent t-test & Wilcoxon-rank sum test used for within cases or controls based on normality.
Sample size for WC, SSAT and SSAT/TAT = 45 for AA and 23 NHW per group.
Sample size for weight stable sub-group: AA = 30 per group (sample for WC and SSAT = 26) and NHW = 19 per group (sample for WC and SSAT = 17).