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. 2017 Jun 24;7(9):2443–2451. doi: 10.7150/thno.18290

Figure 3.

Figure 3

BBR reduced blood lipids in the HFD-fed hamsters but not in those fed with normal diet. (A) After treating HFD-fed hamsters with BBR (oral, 100 mg/kg/day, n=6) for 10 days, the levels of total cholesterol (TC) (L), triglycerides (TG) (M) and LDL-C (R) significantly decreased on day 7 and 10 of the treatment course (**P<0.01, vs day 0; n=6) when compared to that in the hamsters fed with normal diet (vs day 0; n=5); (B) The NR activity of gut microbiota in the HFD-fed hamsters decreased on day 10 after BBR treatment (**P<0.01, n=6); the change was not significant in the ND-fed hamsters (n=6); (C) BBR concentration in plasma decreased on day 7 and 10 of the treatment in the HFD-fed hamsters (*P<0.05, **P<0.01, n=6).