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. 2017 Jun 25;7(9):2524–2536. doi: 10.7150/thno.19856

Figure 4.

Figure 4

(A) In vitro release profiles of EPI form hydrogel (CMC-g-PNIPAAmMA) and hydrogelGd (blends of CMC-g-PNIPAAmMA and DTPAGd/bPEI with different ratios) in PBS (pH 7.4) at 37°C. Values are means ± SD (n = 3). (B) In vitro release profiles of EPI and PTX from BSA/PTX NPs incorporated hydrogelGd/EPI (CMC-g-PNIPAAmMA:DTPAGd/bPEI = 2:1) in PBS (pH 5.6) at 37°C. Values are means ± SD (n = 3). (C) The fluorescence imaging of MBR 614 cells treated with free EPI (5 μg/mL) at 37°C for 3 or 10 h. (D) The fluorescence imaging of MBR 614 cells treated with BSA/FITC incorporated hydrogelGd/EPI (5 μg/mL) at 37°C for 3 or 10 h. (red color: EPI; green color: BSA/FITC NPs; blue color: nuclei).