Table II.
Epigenetic abnormalities in MRKHS.
| Author, year | Gene | Locus | Function | Refs. |
|---|---|---|---|---|
| Miyamoto, 2008 | Wilms tumor gene 1 (WT1) | 11p13 | Sexual determination and control of sexual differentiation | (23) |
| GATA-binding protein 4 (GATA4) | 8p23.1 | Sexual determination and control of sexual differentiation | (23) | |
| Taylor, 2008 | Homeobox A9 (HOXA9) | 7p15.2 | Fallopian tube development | (24) |
| Sauter et al, 2005 | Homeobox A5 (HOXA5) | 7p15.2 | Transcriptional regulation of p53 | (26) |
| Mason et al, 2004 | WNT1 inducible signaling pathway protein 2 (WISP2) | 20q13.12 | Smooth muscle cell proliferation and migration | (28) |
MRKHS, Mayer-Rokitansky-Küster-Hauser syndrome.