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. 2017 Jun 19;14(2):1315–1320. doi: 10.3892/etm.2017.4628

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 3. — Masson staining of paraffin sections was performed on NLC, NLC + CAL, Tg-ERβ, Tg-ERβ + CAL, respectively (myocardial interstitium ×100 magnification, perivascular ×200 magnification). Image-Pro6.0 software was used to analyze the cardiac fibrosis area quantitatively and statistical results were obtained. Compared with the NLC + CAL group, the area of coronary artery and myocardial interstitial fibrosis was significantly reduced in the Tg-ERβ + CAL group, and the difference was statistically significant, *P<0.05. ERβ, estrogen receptor β; NLC, non-transgenic littermate control; CAL, coronary artery ligation.