Table I.
Statistics of echocardiography (mean ± standard deviation).
| Characteristics | NLC | NLC + CAL | Tg-ERβ | Tg-ERβ + CAL |
|---|---|---|---|---|
| No. | 5 | 6 | 5 | 6 |
| BW (g) | 22.7±2.2 | 24.2±1.2 | 24.8±1.2 | 23.8±1.3 |
| HR (bmp) | 412.3±27.7 | 431.4±11.9 | 466.8±28.7 | 428.4±19.6 |
| PWTD (mm)a | 1.17±0.48 | 0.71±0.21 | 0.83±1.24 | 0.67±0.21 |
| PWTS (mm)a | 1.61±0.14 | 1.24±0.21 | 1.42±0.32 | 1.20±0.45 |
| AWTD (mm)a | 0.85±0.12 | 0.72±0.02 | 0.87±0.03 | 0.70±0.11 |
| AWTS (mm)a,b | 1.71±0.13 | 1.31±0.12 | 1.48±0.17 | 1.28±0.21 |
| LVEDD (mm)a | 3.03±0.44 | 3.98±0.24 | 3.52±0.26 | 3.88±0.31 |
| LVESD (mm)a,b | 1.59±0.32 | 2.49±0.31 | 2.16±0.47 | 2.41±0.13 |
| CO (ml/min)a,b | 15.93±5.85 | 18.19±2.43 | 17.25±4.38 | 18.20±3.24 |
| FS (%)a,b | 58.24±2.43 | 37.24±2.19 | 37.10±1.28 | 42.36±1.25 |
| EF (%)a,b | 81.95±2.16 | 67.81±1.33 | 67.42±1.05 | 73.22±1.48 |
| LV mass (AW) correcteda,b | 83.29±11.47 | 82.44±10.96 | 84.34±10.52 | 86.93±13.82 |
a
P<0.05
b
Tg-ERβ was compared with NLC and the differences had statistical significance. NLC, non-transgenic littermate control; ERβ, estrogen receptor β; CAL, coronary artery ligation; BW, body weight; PWTD, posterior wall thickness at end diastole; PWTS, posterior wall thickness at end systolic; AWTD, anterior wall thickness at end diastole; AWTS, anterior wall thickness at end systolic; LVEDD, left ventricular diastolic diameter; LVESD, left ventricular systolic diameter; FS, fractional shortening; EF, ejection fraction; LV, left ventricular.