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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Genomics. 2017 Mar 29;109(3-4):204–213. doi: 10.1016/j.ygeno.2017.03.004

Table 2.

Characteristics of differentially methylated regions (DMRs) detected by MBD-seq and MeDIP-seq assays.

Total DMRs Intersected CGIs DMRs Intersecting Genes*
MBD-seq 769 43 135
Methylation loss 599 43 89
Methylation gain 170 0 46
MeDIP-seq 1771 57 424
Methylation loss 1101 55 219
Methylation gain 670 2 205
Overlap 224 25 23
Methylation loss 198 25 18
Methylation gain 26 0 5

DMRs: Differentially methylated regions. These include adjacent 100bp windows in which DNA methylation levels are significantly different between MAM-treated rats and Saline-control rats at FDR<0.05.

CGI: CpG island. Numbers shown indicate how many DMRs fall within a CGI; in some cases multiple DMRs fall within the same CGI.

*

The number of DMRs that intersect with one (or more) annotated genes (including those of uncertain function, e.g. LOC genes)