Table 2.
| Cmpd |
MRSA
|
E coli
|
|||||
|---|---|---|---|---|---|---|---|
| AG038 | AG039 | AG042 | AG044 | AG001 | AG055 | AG003 | |
|
|
|
||||||
| Parom 4 | 4 (7) | >256 (>417) | >256 (>417) | 4–8 (7–13) | 4 (7) | 2–4 (3–7) | 2–4 (3–7) |
| Neom 6 | 1–2 (2–3) | 128 (209) | 128 (209) | 1 (2) | 2 (3) | 1–2 (2–3) | 1 (2) |
| 5 | 8–16 (12–25) | 16 (25) | 8–16 (12–25) | 8–16 (12–25) | 64 (99) | 32–64 (50–99) | 32 (50) |
| 11 | 4 (6) | 2 (3) | 2 (3) | 1–2 (2–3) | 4 (6) | 2–4 (3–6) | 2–4 (3–6) |
| 21 | 4 (6) | >128 (>195) | >128 (>195) | 2 (3) | 4 (6) | 2–4 (3–6) | 4 (6) |
| 22 | 2 (3) | >128 (>195) | >128 (>195) | 2 (3) | 2–4 (3–6) | 4 (6) | 4 (6) |
| 30 | 4 (7) | >128 (>209) | >128 (>209) | 2 (3) | 4 (7) | 4 (7) | 4 (7) |
| 37 | 8–16 (12–23) | 8 (12) | 4–8 (6–12) | 4–8 (6–12) | 16 (23) | 8–16 (12–23) | 8–16 (12–23) |
| 26 | 8 (11) | >128 (>182) | >128 (>182) | 4 (6) | 16–32 (23–45) | 16 (23) | 16 (23) |
| 28 | 8 (12) | >64 (>97) | >64 (>97) | 8–16 (12–24) | 8 (12) | 8 (12) | 8 (12) |
| 40 | 16 (22) | 16–32 (22–44) | 16 (22) | 16 (22) | 32 (44) | 16–32 (22–44) | 16–32 (22–44) |
| 38 | 32–64 (47–93) | 32–64 (47–93) | 32 (47) | 64 (93) | 64–128 (93–187) | 64–128 (93–187) | 32–64 (93–187) |
a
All values were determined in duplicate using two dilution series.
b
MICs are given in μg/mL and in parentheses in μM.