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. Author manuscript; available in PMC: 2018 May 12.
Published in final edited form as: ACS Infect Dis. 2017 Apr 6;3(5):368–377. doi: 10.1021/acsinfecdis.6b00214

Table 3.

Antibacterial Activities (MIC, μg/mL, (μM))a,b Against ESKAPE Pathogens

Cmpd K pneumoniae
E cloacae
A baumannii.
AG261 AG262 AG263 AG290 AG291 AG292 AG225 AG226 AG286
Parom 4 1 (2) 1 (2) 1 (2) 2 (3) 1–2 (2–3) 2 (3) 4 (7) 2–4 (3–7) 1–2 (2–3)
Neom 6 0.5 (0.8) 0.5 (0.8) 1 (2) 1 (2) 1 (2) 1 (2) 4 (7) 4 (7) 0.5–1 (0.8–2)
5 4 (6) 8 (12) 8 (12) 8–16 (12–25) 8–16 (12–25) 8 (12) 16 (25) 16 (25) 32 (25)
11 0.5 (0.8) 1 (2) 1 (2) 1 (2) 1 (2) 1 (2) 4 (6) 4 (6) 1–2 (2–3)
21 0.5–1 (1–2) 1 (2) 0.5 (1) 1 (2) 1 (2) 1 (2) 2 (3) 2 (3) 1 (2)
22 0.5 (0.8) 0.5 (0.8) 1 (2) 1 (2) 0.5 (0.8) 0.5 (0.8) 2 (3) 2 (3) 0.5 (0.8)
30 0.5 (0.8) 0.5 (0.8) 1 (2) 1 (2) 0.5–1 (0.8–2) 2 (3) 2 (3) 2 (3) 1 (2)
37 2–4 (3–6) 4 (6) 4 (6) 8 (12) 4 (6) 4 (6) 8–16 (12–23) 4–8 (6–12) 8 (12)
a

All values were determined in duplicate using two dilution series.

b

MICs are given in μg/mL and in parentheses in μM.