Table 2.

GO enrichment analysis results of differentially methylated genes between AS patients and healthy controls

GO ID	Description	Genes	P value
GO:0002504	Antigen processing and presentation of peptide or polysaccharide antigen via MHC class II	HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPB1, HLA-DQA1, HLA-DQB1	1.11 × 10–5
GO:0042605	Peptide antigen binding	DHCR24, HLA-A, HLA-B, HLA-C, HLA-DQB1, HLA-DRB1, HLA-H, MAML1, SLC7A5	5.14 × 10–6
GO:0042613	MHC class II protein complex	HLA-DMB, HLA-DOA, HLA-DOB, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRB1	7.97 × 10–6
GO:0071556	Integral to lumenal side of endoplasmic reticulum membrane	CALR, HLA-A, HLA-B, HLA-C, HLA-DPB1, HLA-DQA1, HLA-DQB1, HLA-DRB1	8.79 × 10–5

GO Gene Ontology, AS ankylosing spondylitis