Table 3.

Longitudinal changes in lung function, exercise capacity and physical activity in survivors

Characteristic	Absolute value at baseline	Absolute value at follow-up	Absolute decline (Baseline to follow-up)	Relative decline (Baseline to follow-up)	Average annual decline	p-value
FVC, liter	3.05 (0.81)	2.64 (0.78)	−0.41 (0.33)	13.3%	−0.13 (0.11)	<0.001
FVC, %pred.	84.8 (22.9)	76.1 (23.9)	−8.7 (9.6)	10.5%	−2.8 (3.0)	<0.001
DLCO, %pred.	50.7 (13.6)	43.5 (18.4)	−7.3 (13.3)	14.4%	−2.2 (4.2)	0.024
6MWD, meters	418 (117)	389 (132)	−29 (64)	7.8%	−8.8 (20)	0.055
Steps per day	6499 (3192)	3482 (2350)	−3017 (2372)	48.3%	−973 (743)	<0.001

Data are presented as mean (SD) and % for n = 23 survivors with complete physical activity data at follow-up. Differences between baseline and follow-up visit were tested by paired t-tests. Follow-up data were missing for FVC (n = 1), DLCO (n = 3), and 6MWD (n = 2)

Abbreviations: FVC forced vital capacity, DLCO diffusing capacity of the lung for carbon monoxide, 6MWD 6-min walking-distance