Table 2.
Cut-off values for referral to the home ventilation services
| Suggested values | Guideline values [9, 15, 27] | |||||
|---|---|---|---|---|---|---|
| Cut-off value | Sensitivity | Specificity | Cut-off value | Sensitivity | Specificity | |
| FVC | 95 (77–104) | 85 | 22 | 70 | 65 | 50 |
| PCF | 386 (356–472) | 88 | 36 | 300 | 33 | 67 |
| MIP | 67 (52–74) | 85 | 27 | 60 | 82 | 35 |
| MEP | 74 (66–90) | 85 | 38 | 60 | 68 | 56 |
| SNIP | 45 (41–59) | 87 | 40 | 40 | 71 | 50 |
Cut-off values are presented as value (95% CI). The sensitivity and specificity are calculated with an ROC curve analysis. ALS Amyotrophic Lateral Sclerosis, HVS Home Ventilation Services, NIV Non-invasive ventilation, FVC Forced Vital Capacity (% predicted value), PCF Peak Cough Flow (L/min.), MIP and MEP Maximum Inspiratory and Expiratory Pressure (cm H2O), SNIP Sniff Nasal Inspiratory Pressure (cm H2O)