The proportion of isolates with a defined genotype are shown for South Africa, Ethiopia, Argentina, Portugal, Poland, Iran, Pakistan, India, Nepal, Cambodia, China, Taiwan, and Japan. We classified Beijing genotype strains from South Africa as typical or atypical to show regional differences in the population structure of extensively drug-resistant tuberculosis. Data sources provided in the appendix. LAM=Latino-American-Mediterranean family. CAS=Central-Asian family. T=T family. EAI=East-African-Indian family. U=U family. S=S family. X=X family. H=Haarlem family.