Table 1. Descriptive characteristics of adults per study stratified by sex.
| MDC-CC | IMPROVE | ULSAM | PIVUS | ||||
|---|---|---|---|---|---|---|---|
| Men | Women | Men | Women | Men | Men | Women | |
| nmax | 1915 | 2821 | 1666 | 1780 | 1120 | 474 | 475 |
| Age (years) | 57.7 ± 6.0 | 57.5 ± 5.9 | 64.0 ± 5.4 | 64.4 ± 5.5 | 71.0 ±0.6 | 70.1 ± 0.2 | 70.3 ± 0.1 |
| BMI (kg/m2) | 26.1 ± 3.5 | 25.3 ± 4.2 | 27.4 ± 3.6 | 27.1 ± 4.8 | 26.3 ± 3.4 | 27.0 ± 3.7 | 27.1 ± 4.9 |
| Diastolic blood pressure (mmHg) | 89 ± 9 | 86 ± 9 | 83 ± 10 | 81 ± 10 | 84 ± 9 | 79 ± 10 | 78 ± 10 |
| Systolic blood pressure (mmHg) | 143 ± 19 | 140 ± 19 | 142 ± 18 | 142 ± 19 | 147 ± 19 | 146 ± 22 | 153 ± 23 |
| LDL-cholesterol (mmol/l) | 4.1 ± 0.9 | 4.2 ± 1.0 | 3.4 ± 0.9 | 3.7 ± 1.1 | 3.9 ± 0.9 | 3.2 ± 0.9 | 3.5 ± 0.9 |
| HDL-choleserol (mmol/l) | 1.1 (1.0, 1.4) | 1.5 (1.2, 1.7) | 1.1 (0.9, 1.3) | 1.3 (1.1, 1.6) | 1.2 (1.0, 1.5) | 1.3 (1.1, 1.5) | 1.6 (1.3, 1.9) |
| Current smoking (nsmokers / nnon-smokers) | 510 / 1405 | 716 / 2105 | 279 / 1387 | 238 / 1368 | 222 / 898 | 47 / 426 | 57 / 418 |
| Type 2 diabetes status (cases / controls) | 210 / 1705 | 160 / 2661 | 522 / 1115 | 387 / 1368 | 121 / 998 | 65 / 409 | 46 / 429 |
| IMT CCA (mm) | 0.74 (0.64, 0.85) | 0.70 (0.63, 0.79) | 0.74 (0.66, 0.83) | 0.70 (0.64, 0.77) | 0.71 (0.63, 0.81) | 0.88 (0.79, 1.00) | 0.85 (0.76, 0.97) |
| IMT bulb (mm) | 1.33 (1.02, 1.82) | 1.19 (0.97, 1.56) | 1.13 (0.91, 1.45) | 1.00 (0.80, 1.25) | na | 0.98 (0.89, 1.12) | 0.94 (0.84, 1.07) |
| Plaque presence (cases / controls) | 529 / 827 | 537 / 1372 | 1112 / 547 | 967 / 799 | na | 272 / 202 | 233 / 242 |
| CHD status (cases / controls) | na | na | 76 / 1590 | 45 / 1735 | 316 / 804 | 112 / 362 | 54 / 421 |
IMT, intima-media thickness; CCA, common carotid artery; bulb, also known as sinus; CHD, coronary heart disease; na, not available