Joint Modeling of the Relationships Among BMI, Cerebrovascular Disease, and Alzheimer’s Disease Neuropathology in 1,421 Subject’s from the NACC Neuropathology Data Set. Figure shows that lower BMI significantly predicted higher odds of having Alzheimer’s disease neuropathology. BMI was not associated with the Ischemic Injury Scale, however, higher scores on the Ischemic Injury Scale (worse cerebrovascular disease) predicted greater odds of having Alzheimer’s disease neuropathology. All analyses were controlled for age at death, education, race, sex, and presence of the APOE ε4 allele.